20 Growing Mental Health Startups In 2022

by Josh Howarth
July 29, 2022

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Thanks largely to the global pandemic, 1 in 5 US adults state they experience mental illness. And more than 12M have struggled with serious thoughts of suicide.

What’s more, many struggle to receive the necessary mental health care that they desperately need. To meet this growing demand for mental health services, startups have been crafting creative ways to bridge this gap, including more reliance on telehealth.

This explains the rapid growth in mental health funding, which saw a 139% increase YoY from 2020 to 2021, reaching a record $5.5B.

Most of this growth was spurred by US mental health companies, scoring $4.5B in funding last year. European counterparts raised $651M and Asian companies raised $289M.

With the incidence of mental health conditions only likely to continue to rise, it’s very likely that the mental health startup space will only continue to grow this year. Let’s take a look at some players that could make an impact in this critical space.

1. Meditopia

5-year search growth: 5500%

Search growth status: Regular

Year founded: 2015

Location: Berlin, Germany

Funding: $18.3M (Series A)

What they do: Meditopia is a mental health platform focused on coaching and meditation. The app plays a large role in the user’s experience; today there are over 30M+ users over 120 countries. After completing a mental health assessment, users are provided a personalized program accessible on the app, and can also choose to meet with a mental health coach.

2. NUE Life Health

5-year search growth: 3400%

Search growth status: Regular

Year founded: 2020

Location: Miami, FL

Funding: $26.3M (Series A)

What they do: NUE Life Health is a mental wellness company that offers ketamine therapy to treat mental health disorders including depression, anxiety and PTSD. According to the homepage, the startup has helped deliver over 22.5K treatments to date. Pricing ranges from $1,250 for a 1-month subscription to $2,750 for a 4-month subscription.

3. Elemy

5-year search growth: 2300%

Search growth status: Exploding

Year founded: 2019

Location: San Francisco, CA

Funding $323M (Series B)

What they do: Elemy is a platform that offers physician care to children who have behavioral challenges, including autism, ADHD, PTSD and more. Currently available in 13 states and 57 cities, the startup has reported that children who receive autism care for 6 months see an 80% improvement in behavior.

4. Spring Health

5-year search growth: 20%

Search growth status: Regular

Year founded: 2016

Location: New York, NY

Funding: $295.5M (Series C)

What they do: Spring Health is a B2B mental health startup specifically focused on employee wellbeing. Using machine learning, the company is able to match employees with a care plan that meets their needs. In addition to a care plan, employees have access to a Care Navigator who can offer support through difficult times. Based on Spring Health’s existing clients including Equinox, Instacart and more, 30% of all employees sign up for the program and can recover half a day of productivity each week.

5. Meru Health

5-year search growth: 321%

Search growth status: Regular

Year founded: 2016

Location: San Mateo, CA

Funding: $53.3M (Grant)

What they do: Meru Health is a digital mental health platform that treats people with depression. The startup offers two programs: a 12-week treatment program consisting of therapist and psychiatrist support, a peer support group, meditation practices and a biofeedback device, and a health coaching program consisting of on-demand coach chatting, educational content to reduce stress. Based on one study, 75% of program participants saw a reduction in depression and anxiety symptoms after completing the program.

6. Lyra Health

5-year search growth: 950%

Search growth status: Exploding

Year founded: 2015

Location: Burlingame, CA

Funding: $910.1M (Series F)

What they do: Lyra Health is a B2B company that provides mental healthcare services to employees. Offering a curated network of therapists and coaches, the startup reports a 10x utilization over traditional Employee Assistance Programs (EAPs), as well as over a $2K per member annual reduction in healthcare claims costs.

7. Iris Telehealth

5-year search growth: 235%

Search growth status: Regular

Year founded: 2013

Location: Austin, TX

Funding: $40M (Series B)

What they do: Iris Telehealth is a telepsychiatry platform that provides services to mental health centers and hospitals. Psychiatrists or Psychiatric Nurse Practitioners employed by Iris conduct telemedicine visits or in-person care as needed. The startup has had over 1.5M patient encounters, with a 97% average patient satisfaction rating.

8. Clarigent Health

5-year search growth: 0%

Search growth status: Peaked

Year founded: 2018

Location: Mason, OH

Funding: $1.6M (Grant)

What they do: Clarigent Health is a mental health screening company that leverages machine learning and AI technology to help clinicians make a more informed diagnosis and treatment decisions. Specifically, patient vocal data is measured and assigned a risk score based on the startup’s proprietary natural language processing model. The risk score helps with the early detection of suicide ideation and other behavioral health problems.

9. Eleanor Health

5-year search growth: 195%

Search growth status: Exploding

Year founded: 2019

Location: Waltham, MA

Funding: $82M (Series C)

What they do: Eleanor Health is a comprehensive, in-person and digital mental health provider for mental health and addiction recovery. Currently available in 6 states, the company offers a variety of programs, including medication-assisted treatment, therapy, psychiatry, addiction recovery coaching, telehealth visits and supporting a loved one with an addiction.

10. Workit Health

5-year search growth: 326%

Search growth status: Regular

Year founded: 2015

Location: Ann Arbor, Michigan

Funding: $138.2M (Series C)

What they do: Workit Health is a virtual telemedicine platform that supports people who are recovering from substance addiction. The startup’s program consists of FDA-approved medication to reduce cravings, support groups led by counselors and on-demand messaging with care team coaches. Workit reports an 84% success rate, compared to 33% at traditional rehab centers.

11. Alto Neuroscience

5-year search growth: 50%

Search growth status: Peaked

Year founded: 2019

Location: Los Altos, CA

Funding: $40M (Series A)

What they do: Alto Neuroscience develops psychiatric drugs used to treat mental health conditions. The startup aims to change the current drug development model, which does not consider that different people respond to the same drug differently. Thus, the team uses 10 years of data to match each Alto medicine with each patient, creating a better fit. Currently, the studies are focused on depression and PTSD, but will soon expand to other conditions.

12. Mantra Health

5-year search growth: 30%

Search growth status: Regular

Year founded: 2018

Location: New York, NY

Funding: $29.2M (Series A)

What they do: Mantra Health offers digital mental health services for university students. By partnering with each college’s campus counseling centers, students can access therapy, and resources to help foster positive lifestyle changes and medication. Patient outcomes have shown clinical improvement exceeding industry standards within 4 weeks of treatment, and even more pronounced improvement after 12 weeks of treatment.

13. Concert Health

5-year search growth: 142%

Search growth status: Regular

Year founded: 2016

Location: San Diego, CA

Funding: $56.5M (Series B)

What they do: Concert Health is a behavioral health medical group that helps providers and health plans integrate behavioral health into their services. Patients meet with a Behavioral Care Manager (BCM) to set goals, receive counseling and monitor their treatment plan. Available in 12 states, the startup has helped over 24K patients get care.

14. Brightline

5-year search growth: 338%

Search growth status: Regular

Year founded: 2019

Location: Palo Alto, CA

Funding: $212M (Series C)

What they do: Brightline is a virtual care platform that serves children, teens and their families. Using the Connect app, families can find resources to support their kids, as well as on-demand messaging with coaches. Kids can also sign up for one-on-one coaching sessions to help them through stress, breakups, school and more.

15. Hurdle

5-year search growth: 250%

Search growth status: Regular

Year founded: 2018

Location: Washington, DC

Funding: $5M (Seed)

What they do: Hurdle is a B2B startup that has developed an app to help employers find ways to manage stress. Employers complete a short form to register for therapy and can join sessions from their mobile device or computer. Hurdle emphasizes the importance of recognizing cultural differences and provides Culturally Intentional Therapy to meet the needs of people of color and minority groups.

16. Heard

5-year search growth: 18%

Search growth status: Exploding

Year founded: 2019

Location: San Francisco, CA

Funding: $11.3M (Series A)

What they do: Heard is a platform that combines software and accountants to provide therapists with accounting and tax solutions. Heard is able to connect with banks, credit cards and payment platforms, such as Paypal. The service is priced at $149 per month for solo practices and $249 per month for group practices.

17. Parsley Health

5-year search growth: 41%

Search growth status: Regular

Year founded: 2016

Location: New York, NY

Funding: $36M (Series B)

What they do: Parsley Health is a primary care platform that offers treatment for a wide range of conditions and stages of life, ranging from mental health to digestion to pregnancy. A 12-month membership includes 5 visits with a clinician and 5 visits with a health coach, as well as other perks. 80% of members report feeling better within the first year, and 77% reduce their number of prescriptions.

18. Kintsugi

5-year search growth: 211%

Search growth status: Regular

Year founded: 2019

Location: Berkeley, CA

Funding: $29.3M (Series A)

What they do: Kintsugi is a platform for health systems, payors and providers that screens speech clips for depression and anxiety. Currently available in 250+ cities around the world, the startup offers a talk therapy app that utilizes its proprietary KiVA (Kintsugi Voice Biomarker API) technology to detect mental health conditions as well as other health markers, such as sleep quality, nutrition and emotional triggers.

19. Modern Health

5-year search growth: 55%

Search growth status: Regular

Year founded: 2017

Location: San Francisco, CA

Funding: $167.4M (Series D)

What they do: Modern Health is a B2B app for employers that want to offer their employees therapy, coaching and educational content. Coaches and therapists are available in over 50 languages and use evidence-based techniques with members. 75% of engaged app users have reported that the program helps them maintain and improve their well-being.

20. Zencare

5-year search growth: 400%

Search growth status: Exploding

Year founded: 2015

Location: Brooklyn, NY

Funding: Undisclosed

What they do: Zencare is a platform that helps you find the best therapist for your needs. Patients can book a free initial consultation to ensure that they’ve found a suitable therapist. The startup ensures that its network of therapists has been properly vetted and also manages patients’ insurance information.


That wraps up our list of mental health startups that are showing great potential for continued growth in 2022.

One thing is clear: these companies are aiming to build better experiences for their patients. Through personalization and one-on-one connection with a therapist or coach, patients are more likely to feel more supported as they navigate the confusing waters that are mental health.

These startups are also leveraging more technology and AI to deliver more accurate diagnoses and longer-lasting clinical outcomes. From natural language processing to machine learning algorithms, the more data that startups collect, the more accurate their results will become.

Mental health has a huge ripple effect. To name just two effects: those with serious mental conditions are twice as likely to develop cardiometabolic diseases and depression and anxiety disorders result in $1T lost productivity every year worldwide.

With mental health having such a huge impact on healthcare costs, economic productivity and quality of life, it’s likely that more mental health startups will continue to spring up in 2022.