Top Trending Health & Wellness Startups in San Francisco

In November, several emerging startups have taken off in the health space in San Francisco. Leading the charge is rootly, the top trending topic, with a search volume of 3.6K and an impressive +326% growth rate.

TOP COMPANIES - UPDATED NOV 2025
45 Results

1. rootly

Exploding Growth

Software company specializing in 'Incident Management as a Service,' offering solutions for multi-cloud on-call management. Rootly differentiates itself by enabling seamless collaboration in Slack, consolidating alerts,…

Startup Details
San Francisco
Location
Nov 2020
Founded Date
Data & Forecast
+326%
2 years Growth
3.6K/mo
Search Volume
businesstechnologyhealthproductivityaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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2. Cal ai

Exploding Growth

Cal AI is a calorie counter application that utilizes artificial intelligence to assist users in managing their meals and tracking carbohydrate intake. It differentiates itself by providing personalized meal…

Startup Details
San Francisco
Location
May 2024
Founded Date
Data & Forecast
+1160%
2 years Growth
22.2K/mo
Search Volume
technologyhealthsoftwareainutritiondiets
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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3. Included Health Inc.

Regular Growth

Company that offers a unique combination of virtual care, navigation, and community-based healthcare services. Included Health Inc. aims to help organizations deliver a significantly improved healthcare experience to…

Startup Details
San Francisco
Location
Jan 2011
Founded Date
Data & Forecast
+6600%
2 years Growth
0-100/mo
Search Volume
businesstechnologyhealthhealthcareai
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

4. Teal health

Exploding Growth

Company dedicated to enhancing cervical cancer screening through innovative solutions. It offers the Teal Wand, a product that enables self-sampling and testing using an FDA-approved Primary HPV test, distinguishing…

Startup Details
San Francisco
Location
Jan 2020
Founded Date
Data & Forecast
+588%
2 years Growth
8.1K/mo
Search Volume
businesshealthhealthcarepharmaproductivity
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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5. Wild ai

Exploding Growth

Mobile application designed to help users, particularly women, track their hormones and training through self-reported symptoms and wearable data. It aims to enhance performance and prevent health issues by offering…

Startup Details
San Francisco
Location
Mar 2017
Founded Date
Data & Forecast
+671%
2 years Growth
1K/mo
Search Volume
technologyhealthfitnessaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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6. Arctop

Regular Growth

Company specializing in mapping and measuring brain signals from both peak performing experts and novices. Their technology enables personalized training that aims to shorten the learning curve, particularly in skill…

Startup Details
San Francisco
Location
Jun 2016
Founded Date
Data & Forecast
+1000%
2 years Growth
320/mo
Search Volume
businesstechnologyscienceaiprogramminghealthmental-healthgamingeducation
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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7. Hinge Health

Exploding Growth

A company founded in 2014 by Daniel Perez and Gabriel Mecklenburg, focused on making high-quality musculoskeletal (MSK) care accessible. It provides digital solutions for chronic pain management, particularly for back…

Startup Details
San Francisco
Location
Jan 2015
Founded Date
Data & Forecast
+225%
2 years Growth
49.5K/mo
Search Volume
technologyhealthhealthcaretelecommunication
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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8. Viz ai

Exploding Growth

Founded in 2016, this company leverages artificial intelligence to enhance healthcare efficiency and patient outcomes. It differentiates itself by providing AI-driven solutions that streamline the diagnosis and…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+280%
2 years Growth
3.6K/mo
Search Volume
technologyhealthaihealthcareautomation
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

9. Forager Project

Exploding Growth

A family-owned organic food company that has been producing plant-based foods since 2013. The company focuses on improving human and planetary health by creating dairy-free, organic plant-based products, differentiating…

Startup Details
San Francisco
Location
Jan 2013
Founded Date
Data & Forecast
+140%
2 years Growth
1.6K/mo
Search Volume
businesshealthfood-beveragefoodcpgnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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10. OneSkin

Exploding Growth

Longevity-focused company developing products aimed at extending skin and body health by targeting the aging process. OneSkin differentiates itself by utilizing principles of aging and longevity science to create…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+133%
2 years Growth
33.1K/mo
Search Volume
businessbeautyhealthretailskincarepersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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11. Viz.ai

Exploding Growth

Company that offers AI-powered care coordination solutions, utilizing advanced algorithms to analyze medical imaging data such as CT scans and EKGs. Viz.ai's technology aims to improve the efficiency and accuracy of…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+400%
2 years Growth
4.4K/mo
Search Volume
businesstechnologyhealthaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

12. MDacne

Exploding Growth

Personalized skincare service that formulates customized anti-acne treatment creams. These creams are designed to clear current blemishes, prevent new ones from forming, and help fade post-acne brown spots, all while…

Startup Details
San Francisco
Location
Dec 2016
Founded Date
Data & Forecast
+82%
2 years Growth
14.8K/mo
Search Volume
businessbeautyhealthskincarehealthcareretail
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

13. Modern Health

Exploding Growth

Evidence-based, global mental health solution designed for employers. It aims to deliver tangible results, such as lower costs and meaningful outcomes, for both employers and their employees by offering a fully…

Startup Details
San Francisco
Location
Jan 2017
Founded Date
Data & Forecast
+254%
2 years Growth
12.1K/mo
Search Volume
businesshealthindustryworkplacehealthcaremental-health
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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14. ZBiotics

Exploding Growth

Patented, genetically engineered probiotic designed to help mitigate the effects of alcohol consumption. It works by breaking down acetaldehyde, a byproduct of alcohol that is primarily responsible for hangover…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+98%
2 years Growth
49.5K/mo
Search Volume
businesshealthfood-beveragesupplementsalcoholbeverages
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

15. Milo ai

Exploding Growth

​Milo is a digital assistant designed to help families manage daily tasks and responsibilities. It offers features such as shared calendars, to-do lists, and reminders, aiming to streamline household organization and…

Startup Details
San Francisco
Location
Jan 2019
Founded Date
Data & Forecast
+430%
2 years Growth
480/mo
Search Volume
technologyhealthlifestyleaibabyhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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16. Komodo Health

Exploding Growth

A company that offers software solutions for healthcare systems, focusing on data, diagnosis, and treatments. It provides a comprehensive view of the U.S. healthcare system through its Healthcare Map, which combines…

Startup Details
San Francisco
Location
Jan 2014
Founded Date
Data & Forecast
+174%
2 years Growth
6.6K/mo
Search Volume
businesstechnologyhealthproductivityhealthcareai
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

17. Trusted Health

Exploding Growth

Platform that connects healthcare professionals, including nurses and allied health professionals, to over 20,000 personalized travel job opportunities. Trusted Health emphasizes transparency, support, and community…

Startup Details
San Francisco
Location
Jan 2017
Founded Date
Data & Forecast
+246%
2 years Growth
4.4K/mo
Search Volume
businesshealthhealthcareworkplace
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

18. DripDrop

Exploding Growth

Electrolyte powder brand designed to aid in hydration, available in various flavors and pack sizes. DripDrop differentiates itself by offering a medically-formulated solution that is both effective and palatable, making…

Startup Details
San Francisco
Location
Jan 2008
Founded Date
Data & Forecast
+110%
2 years Growth
40.5K/mo
Search Volume
businesshealthecommerceretailsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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19. Jen water

Exploding Growth

Flavored water product infused with marine collagen peptides and aloe vera, designed to promote skin health and hydration. Jen water differentiates itself by combining collagen, which stimulates the body's natural…

Startup Details
San Francisco
Location
Jan 2009
Founded Date
Data & Forecast
+110%
2 years Growth
140/mo
Search Volume
healthfood-beveragebeveragesnutritionpersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

20. Brightside health

Exploding Growth

A mental health care provider offering online therapy and medication management services. It focuses on providing accessible and affordable care for conditions such as anxiety and depression, with services including…

Startup Details
San Francisco
Location
Jan 2017
Founded Date
Data & Forecast
+97%
2 years Growth
22.2K/mo
Search Volume
technologyhealthhealthcaremental-healthtelecommunication
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

21. Irhythm technologies

Exploding Growth

Digital healthcare company specializing in solutions to detect, predict, and prevent disease through wearable biosensors and cloud-based data analytics. Irhythm Technologies differentiates itself with its Zio ambulatory…

Startup Details
San Francisco
Location
Jan 2006
Founded Date
Data & Forecast
+86%
2 years Growth
12.1K/mo
Search Volume
businesstechnologyhealthhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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22. Calico labs

Exploding Growth

Research and development company focused on understanding the biological pathways of aging and disease. The company differentiates itself by fostering collaboration and interdisciplinary research, supported by advanced…

Startup Details
San Francisco
Location
Sep 2013
Founded Date
Data & Forecast
+67%
2 years Growth
1.6K/mo
Search Volume
businesshealthsciencepharmahealthcareproductivity
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

23. Grand Rounds Health

Exploding Growth

Healthcare company that merged with Doctor On Demand to form Included Health, aiming to enhance the member experience and improve clinical and financial outcomes. Grand Rounds Health differentiates itself by integrating…

Startup Details
San Francisco
Location
Jan 2011
Founded Date
Data & Forecast
+111%
2 years Growth
390/mo
Search Volume
businesshealthhealthcareworkplace
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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24. Allermi

Peaked Growth

Service offering custom allergy treatments designed by board-certified allergists, backed by scientific research. These treatments are delivered directly to the customer's door and use custom combinations and doses of…

Startup Details
San Francisco
Location
Jan 2019
Founded Date
Data & Forecast
+4%
2 years Growth
5.4K/mo
Search Volume
healthpharmahealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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25. Heard accounting

Exploding Growth

All-in-one financial solution designed specifically for therapists, combining software and human support to handle various financial tasks. Heard accounting differentiates itself by offering specialized services such as…

Startup Details
San Francisco
Location
Jan 2019
Founded Date
Data & Forecast
+126%
2 years Growth
480/mo
Search Volume
businesstechnologyhealthfinancepersonal-financehealthcarehr
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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Showing 1-25 of 45 Results

About Health & Wellness in San Francisco

Interest in Health startups in San Francisco continues to surge this November. Leading the charge is rootly, founded in Nov 2020, with 3.6K monthly searches and an impressive +326% growth. Runner-up Cal ai, launched in May 2024, also shows strong engagement with 22.2K people searching for it each month. Included Health Inc. rounds out the top three. Established in Jan 2011, they’ve built steady momentum, seeing 0-100 monthly searches and +6600% growth. Together, these rising brands highlight how San Francisco’s Health startups are becoming increasingly attractive to both consumers and investors.

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