Top Trending Health & Wellness Startups in San Francisco

In December, several emerging startups have taken off in the health space in San Francisco. Leading the charge is Cal ai, the top trending topic, with a search volume of 22.2K and an impressive +1325% growth rate.

TOP COMPANIES - UPDATED DEC 2025
35 Results

1. Cal ai

Exploding Growth

Cal AI is a calorie counter application that utilizes artificial intelligence to assist users in managing their meals and tracking carbohydrate intake. It differentiates itself by providing personalized meal…

Startup Details
San Francisco
Location
May 2024
Founded Date
Data & Forecast
+1325%
2 years Growth
22.2K/mo
Search Volume
technologyhealthsoftwareainutritiondiets
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

2. Wild ai

Peaked Growth

Mobile application designed to help users, particularly women, track their hormones and training through self-reported symptoms and wearable data. It aims to enhance performance and prevent health issues by offering…

Startup Details
San Francisco
Location
Mar 2017
Founded Date
Data & Forecast
+186%
2 years Growth
1K/mo
Search Volume
technologyhealthfitnessaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

3. Teal health

Exploding Growth

Company dedicated to enhancing cervical cancer screening through innovative solutions. It offers the Teal Wand, a product that enables self-sampling and testing using an FDA-approved Primary HPV test, distinguishing…

Startup Details
San Francisco
Location
Jan 2020
Founded Date
Data & Forecast
+656%
2 years Growth
8.1K/mo
Search Volume
businesshealthhealthcarepharmaproductivity
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

4. rootly

Exploding Growth

Software company specializing in 'Incident Management as a Service,' offering solutions for multi-cloud on-call management. Rootly differentiates itself by enabling seamless collaboration in Slack, consolidating alerts,…

Startup Details
San Francisco
Location
Nov 2020
Founded Date
Data & Forecast
+104%
2 years Growth
3.6K/mo
Search Volume
businesstechnologyhealthproductivityaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

5. Modern Health

Exploding Growth

Evidence-based, global mental health solution designed for employers. It aims to deliver tangible results, such as lower costs and meaningful outcomes, for both employers and their employees by offering a fully…

Startup Details
San Francisco
Location
Jan 2017
Founded Date
Data & Forecast
+107%
2 years Growth
12.1K/mo
Search Volume
businesshealthindustryworkplacehealthcaremental-health
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

6. Included Health Inc.

Regular Growth

Company that offers a unique combination of virtual care, navigation, and community-based healthcare services. Included Health Inc. aims to help organizations deliver a significantly improved healthcare experience to…

Startup Details
San Francisco
Location
Jan 2011
Founded Date
Data & Forecast
+2600%
2 years Growth
0-100/mo
Search Volume
businesstechnologyhealthhealthcareai
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

7. Viz ai

Exploding Growth

Founded in 2016, this company leverages artificial intelligence to enhance healthcare efficiency and patient outcomes. It differentiates itself by providing AI-driven solutions that streamline the diagnosis and…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+293%
2 years Growth
3.6K/mo
Search Volume
technologyhealthaihealthcareautomation
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

8. Hinge Health

Exploding Growth

A company founded in 2014 by Daniel Perez and Gabriel Mecklenburg, focused on making high-quality musculoskeletal (MSK) care accessible. It provides digital solutions for chronic pain management, particularly for back…

Startup Details
San Francisco
Location
Jan 2015
Founded Date
Data & Forecast
+67%
2 years Growth
49.5K/mo
Search Volume
technologyhealthhealthcaretelecommunication
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

9. Ombre health

Peaked Growth

Company specializing in gut health, offering microbiome testing kits that provide personalized reports and recommendations based on the analysis of an individual's gut bacteria. Ombre Health differentiates itself by…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+90%
2 years Growth
30/mo
Search Volume
businesshealthecommerceretailsupplementshealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

Get Advanced Insights on Any Topic

Discover Trends 12+ Months Before Everyone Else

Try Exploding Topics Pro
7 Day Free Trial

10. Trusted Health

Exploding Growth

Platform that connects healthcare professionals, including nurses and allied health professionals, to over 20,000 personalized travel job opportunities. Trusted Health emphasizes transparency, support, and community…

Startup Details
San Francisco
Location
Jan 2017
Founded Date
Data & Forecast
+86%
2 years Growth
4.4K/mo
Search Volume
businesshealthhealthcareworkplace
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

11. Viz.ai

Peaked Growth

Company that offers AI-powered care coordination solutions, utilizing advanced algorithms to analyze medical imaging data such as CT scans and EKGs. Viz.ai's technology aims to improve the efficiency and accuracy of…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+86%
2 years Growth
4.4K/mo
Search Volume
businesstechnologyhealthaihealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

12. Milo ai

Peaked Growth

​Milo is a digital assistant designed to help families manage daily tasks and responsibilities. It offers features such as shared calendars, to-do lists, and reminders, aiming to streamline household organization and…

Startup Details
San Francisco
Location
Jan 2019
Founded Date
Data & Forecast
+50%
2 years Growth
480/mo
Search Volume
technologyhealthlifestyleaibabyhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

13. Forward health

Exploding Growth

Revolutionary primary care service that focuses on long-term health by combining top-rated doctors with advanced technology. Forward Health differentiates itself by offering personalized care through its CarePod, which…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+57%
2 years Growth
18.1K/mo
Search Volume
businesstechnologyhealthhealthcareai
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

14. OneSkin

Exploding Growth

Longevity-focused company developing products aimed at extending skin and body health by targeting the aging process. OneSkin differentiates itself by utilizing principles of aging and longevity science to create…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+97%
2 years Growth
33.1K/mo
Search Volume
businessbeautyhealthretailskincarepersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

15. Arctop

Peaked Growth

Company specializing in mapping and measuring brain signals from both peak performing experts and novices. Their technology enables personalized training that aims to shorten the learning curve, particularly in skill…

Startup Details
San Francisco
Location
Jun 2016
Founded Date
Data & Forecast
+700%
2 years Growth
320/mo
Search Volume
businesstechnologyscienceaiprogramminghealthmental-healthgamingeducation
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

16. Komodo Health

Peaked Growth

A company that offers software solutions for healthcare systems, focusing on data, diagnosis, and treatments. It provides a comprehensive view of the U.S. healthcare system through its Healthcare Map, which combines…

Startup Details
San Francisco
Location
Jan 2014
Founded Date
Data & Forecast
+33%
2 years Growth
6.6K/mo
Search Volume
businesstechnologyhealthproductivityhealthcareai
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

17. Forager Project

Exploding Growth

A family-owned organic food company that has been producing plant-based foods since 2013. The company focuses on improving human and planetary health by creating dairy-free, organic plant-based products, differentiating…

Startup Details
San Francisco
Location
Jan 2013
Founded Date
Data & Forecast
+22%
2 years Growth
1.6K/mo
Search Volume
businesshealthfood-beveragefoodcpgnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

18. Calico labs

Exploding Growth

Research and development company focused on understanding the biological pathways of aging and disease. The company differentiates itself by fostering collaboration and interdisciplinary research, supported by advanced…

Startup Details
San Francisco
Location
Sep 2013
Founded Date
Data & Forecast
+85%
2 years Growth
1.6K/mo
Search Volume
businesshealthsciencepharmahealthcareproductivity
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

Get Advanced Insights on Any Topic

Discover Trends 12+ Months Before Everyone Else

Try Exploding Topics Pro
7 Day Free Trial

19. ZBiotics

Exploding Growth

Patented, genetically engineered probiotic designed to help mitigate the effects of alcohol consumption. It works by breaking down acetaldehyde, a byproduct of alcohol that is primarily responsible for hangover…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+148%
2 years Growth
49.5K/mo
Search Volume
businesshealthfood-beveragesupplementsalcoholbeverages
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

20. MDacne

Exploding Growth

Personalized skincare service that formulates customized anti-acne treatment creams. These creams are designed to clear current blemishes, prevent new ones from forming, and help fade post-acne brown spots, all while…

Startup Details
San Francisco
Location
Dec 2016
Founded Date
Data & Forecast
+13%
2 years Growth
14.8K/mo
Search Volume
businessbeautyhealthskincarehealthcareretail
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

21. Jen water

Exploding Growth

Flavored water product infused with marine collagen peptides and aloe vera, designed to promote skin health and hydration. Jen water differentiates itself by combining collagen, which stimulates the body's natural…

Startup Details
San Francisco
Location
Jan 2009
Founded Date
Data & Forecast
+26%
2 years Growth
140/mo
Search Volume
healthfood-beveragebeveragesnutritionpersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

22. DripDrop

Exploding Growth

Electrolyte powder brand designed to aid in hydration, available in various flavors and pack sizes. DripDrop differentiates itself by offering a medically-formulated solution that is both effective and palatable, making…

Startup Details
San Francisco
Location
Jan 2008
Founded Date
Data & Forecast
+46%
2 years Growth
40.5K/mo
Search Volume
businesshealthecommerceretailsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

23. PicnicHealth

Peaked Growth

A company that specializes in collecting and organizing medical records into a secure, digital timeline. It aims to empower patients by providing easy access to their medical history and enabling them to contribute to…

Startup Details
San Francisco
Location
Jan 2014
Founded Date
Data & Forecast
+20%
2 years Growth
3.6K/mo
Search Volume
businesstechnologyhealthhealthcareproductivity
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

24. Heard accounting

Exploding Growth

All-in-one financial solution designed specifically for therapists, combining software and human support to handle various financial tasks. Heard accounting differentiates itself by offering specialized services such as…

Startup Details
San Francisco
Location
Jan 2019
Founded Date
Data & Forecast
+16%
2 years Growth
480/mo
Search Volume
businesstechnologyhealthfinancepersonal-financehealthcarehr
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

25. melixir

Exploding Growth

Company that creates plant-based skincare products rooted in Korean culture. Inspired by the power of Asian medicinal plants, it aims to deliver high-quality products with clinically proven results, differentiating…

Startup Details
San Francisco
Location
Jan 2018
Founded Date
Data & Forecast
+39%
2 years Growth
2.4K/mo
Search Volume
businessbeautyhealthretailmakeup-cosmeticsskincare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial
Showing 1-25 of 35 Results

About Health & Wellness in San Francisco

Interest in Health startups in San Francisco continues to surge this December. Leading the charge is Cal ai, founded in May 2024, with 22.2K monthly searches and an impressive +1325% growth. Runner-up Wild ai, launched in Mar 2017, also shows strong engagement with 1K people searching for it each month. Teal health rounds out the top three. Established in Jan 2020, they’ve built steady momentum, seeing 8.1K monthly searches and +656% growth. Together, these rising brands highlight how San Francisco’s Health startups are becoming increasingly attractive to both consumers and investors.

Explore More Startups

Discover Trends 12+ Months Before Everyone Else

Reveal More Competitor Secrets for Free

Which keywords they target
Their most important pages
Where they get backlinks from
How they monetize their site
Get more free data