Top Trending Vitamins & Supplements Startups

In December, several emerging startups have taken off in the supplements space. Leading the charge is Gruns, the top trending topic, with a search volume of 90.5K and an impressive +745% growth rate.

TOP COMPANIES - UPDATED DEC 2025
105 Results

1. Gruns

Exploding Growth

Daily greens gummies designed to support gut health, immune function, brain and memory support, and overall wellness. These gummies are formulated with a variety of vitamins, minerals, and nutrient-dense ingredients,…

Startup Details
Stanford
Location
Jan 2023
Founded Date
Data & Forecast
+745%
2 years Growth
90.5K/mo
Search Volume
supplementsnutritionhealthfood-beverageecommercecpg
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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2. Odyssey Elixir

Exploding Growth

Nootropic product designed to enhance cognitive functions such as memory, focus, and learning. It utilizes a high concentration of active mushroom compounds, particularly from Lion's Mane, known for its cognitive…

Startup Details
Margate City
Location
Jan 2020
Founded Date
Data & Forecast
+463%
2 years Growth
1.6K/mo
Search Volume
healthsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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3. Create creatine

Exploding Growth

​Create Wellness is a New York-based company specializing in creatine-based supplements, notably offering the world's first creatine monohydrate gummies. Their products utilize Creapure® creatine monohydrate and are NSF…

Startup Details
New York
Location
Jan 2022
Founded Date
Data & Forecast
+522%
2 years Growth
5.4K/mo
Search Volume
healthfitnesssupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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4. Fera pets

Exploding Growth

Brand offering veterinarian-created pet health supplements, including probiotics, joint support chews, and dental powders. It focuses on organic and high-quality ingredients to enhance pet health and well-being,…

Startup Details
Glendale
Location
Jan 2017
Founded Date
Data & Forecast
+600%
2 years Growth
1.3K/mo
Search Volume
healthlifestylesupplementspetsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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5. Perelel

Exploding Growth

Health and wellness company providing prenatal vitamins and supplements tailored for various stages of pregnancy, along with multivitamins for men. Perelel differentiates itself by offering stage-specific formulations…

Startup Details
Los Angeles
Location
Jan 2018
Founded Date
Data & Forecast
+218%
2 years Growth
18.1K/mo
Search Volume
businesshealthsupplementshealthcarenutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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6. Joyspring

Exploding Growth

This brand offers natural vitamins and supplements specifically designed for children, addressing health concerns such as flu prevention and focus enhancement. Joyspring is distinguished by its commitment to…

Startup Details
Waxhaw
Location
Apr 2016
Founded Date
Data & Forecast
+643%
2 years Growth
3.6K/mo
Search Volume
healthecommercesupplementsnutritionhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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7. Zooki

Exploding Growth

Brand specializing in health products, including liposomal and collagen supplements, recognized for their effectiveness and award-winning formulations. Zooki differentiates itself by offering innovative delivery methods…

Startup Details
London
Location
Jan 2017
Founded Date
Data & Forecast
+114%
2 years Growth
12.1K/mo
Search Volume
healthsupplementsnutritionhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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8. Function health

Exploding Growth

Healthcare technology company offering an insurance-free model with transparent pricing. Function Health partners with independent providers to deliver laboratory and medical services, aiming to simplify access to…

Startup Details
Austin
Location
Jan 2022
Founded Date
Data & Forecast
+414%
2 years Growth
90.5K/mo
Search Volume
healthlifestylehealthcaresupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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9. Real vitamins

Exploding Growth

Real vitamins are dietary supplements made from whole food sources, designed to support various aspects of health. These vitamins aim to provide essential nutrients in a natural form, differentiating themselves from…

Startup Details
Tampa
Location
Jan 2021
Founded Date
Data & Forecast
+156%
2 years Growth
170/mo
Search Volume
healthsupplementsnutritionpersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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10. Heart & soil

Exploding Growth

Heart & Soil is a company founded by Dr. Paul Saladino that focuses on promoting health through an animal-based diet. The company offers supplements derived from animal organs, aiming to provide essential nutrients that…

Startup Details
Austin
Location
Jan 2020
Founded Date
Data & Forecast
+83%
2 years Growth
33.1K/mo
Search Volume
healthsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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11. Truemed

Exploding Growth

Payment mechanism that enables health and wellness businesses to accept HSA/FSA funds. Truemed can be deployed easily, often in under 30 minutes, without requiring any engineering effort from the business, making it a…

Startup Details
South San Francisco
Location
Jan 2011
Founded Date
Data & Forecast
+335%
2 years Growth
27.1K/mo
Search Volume
healthfitnesssupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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12. Bravenly

Exploding Growth

Health and wellness company co-founded by Aspen Emry, focusing on products formulated by naturopathic doctors. The company offers a range of products, including adaptogenic blends for hormonal balance and sexual…

Startup Details
Clearwater
Location
Jan 2020
Founded Date
Data & Forecast
+481%
2 years Growth
60.5K/mo
Search Volume
supplementsnutritionhealthpersonal-care
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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13. Cornbread hemp

Exploding Growth

Cornbread Hemp is a company that specializes in hemp-derived CBD products, offering full-spectrum, flower-only, and USDA organic options. The company emphasizes the natural medicinal benefits of cannabis, aiming to make…

Startup Details
Louisville
Location
Jan 2019
Founded Date
Data & Forecast
+171%
2 years Growth
5.4K/mo
Search Volume
businesshealthecommerceretailsupplementshealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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14. Create Wellness

Exploding Growth

Create Wellness is a company that produces creatine monohydrate supplements in gummy form. These gummies are designed to improve muscle strength, recovery, and cognitive performance, offering a convenient alternative to…

Startup Details
New York
Location
Jan 2022
Founded Date
Data & Forecast
+81%
2 years Growth
2.4K/mo
Search Volume
supplementsnutritionpersonal-carehealth
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

15. Hiya health

Exploding Growth

A company that focuses on providing children's vitamins, known for offering a chewable vitamin free from added sugars, artificial ingredients, and common allergens. The vitamins are formulated to support children's…

Startup Details
Anaheim
Location
Jan 2012
Founded Date
Data & Forecast
+274%
2 years Growth
6.6K/mo
Search Volume
healthlifestylesupplementsnutritionhealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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16. Transparent Labs

Exploding Growth

A company based in American Fork, Utah, that produces and retails health and body growth supplements. They offer a range of products including bulk and lean pre-workout supplements and proteins, known for being free…

Startup Details
New York
Location
Jan 2015
Founded Date
Data & Forecast
+130%
2 years Growth
135K/mo
Search Volume
businesshealthretailfitnesssupplements
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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17. Front of the pack

Exploding Growth

Front of the Pack is a company that specializes in supplements and air-dried dog food made with high-quality ingredients. Their products are 100% natural and sustainable, containing no fillers or byproducts, which…

Startup Details
Los Angeles
Location
Oct 2019
Founded Date
Data & Forecast
+67%
2 years Growth
590/mo
Search Volume
businesshealthlifestylepetsretailsupplements
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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18. Toniiq

Exploding Growth

Company specializing in the creation of highly concentrated bioactive compounds. Toniiq differentiates itself by offering ultra high potency products, such as their reishi mushroom supplement, which is designed for…

Startup Details
New York
Location
Jan 2013
Founded Date
Data & Forecast
+67%
2 years Growth
1.6K/mo
Search Volume
healthsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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19. Nutricost

Exploding Growth

Company that offers a variety of dietary supplements, including protein, vitamin, and mineral supplements. Nutricost differentiates itself by providing high-quality, affordable supplements that cater to various health…

Startup Details
Orem
Location
Jan 2012
Founded Date
Data & Forecast
+225%
2 years Growth
60.5K/mo
Search Volume
businesshealthretailsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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20. mybacs

Exploding Growth

Research-driven direct-to-consumer (DTC) company specializing in the human microbiome. Mybacs aims to revolutionize the market around intestinal healthcare by offering products that contribute to the daily well-being of…

Startup Details
Baar
Location
Jan 2019
Founded Date
Data & Forecast
+119%
2 years Growth
33.1K/mo
Search Volume
businesshealthecommerceretailhealthcaresupplements
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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21. Ombre health

Peaked Growth

Company specializing in gut health, offering microbiome testing kits that provide personalized reports and recommendations based on the analysis of an individual's gut bacteria. Ombre Health differentiates itself by…

Startup Details
San Francisco
Location
Jan 2016
Founded Date
Data & Forecast
+90%
2 years Growth
30/mo
Search Volume
businesshealthecommerceretailsupplementshealthcare
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

22. One earth health

Exploding Growth

Company specializing in high-quality beef tallow and beef organ supplements aimed at promoting natural health, energy, and focus. One Earth Health differentiates itself by emphasizing ancestral nutrition and offering…

Startup Details
Scottsdale
Location
Jan 2013
Founded Date
Data & Forecast
+74%
2 years Growth
170/mo
Search Volume
businesshealthfood-beverageretailsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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23. Essential stacks

Regular Growth

Gut health company that designs supplements aimed at addressing digestive issues such as bloating, leaky gut, and overall digestive health. Essential Stacks differentiates itself by formulating products that support…

Startup Details
United States
Location
Jan 2016
Founded Date
Data & Forecast
+1900%
2 years Growth
90/mo
Search Volume
healthsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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24. Bare Biology

Exploding Growth

Company founded in 2012 that specializes in producing high-quality Omega-3 fish oil supplements, algae oils, marine collagen, and vitamin D. The company is well-regarded by nutritional therapists, health experts, and…

Startup Details
Brighton
Location
Jan 2013
Founded Date
Data & Forecast
+62%
2 years Growth
8.1K/mo
Search Volume
businesshealthretailsupplementsnutrition
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
Start 7-Day Free Trial

25. Better & Better

Exploding Growth

Company that offers premium oral care products made with natural, clean, and vegan ingredients. Better & Better differentiates itself by enhancing its products with vitamins for improved oral health, aiming to benefit…

Startup Details
New York
Location
Jan 2019
Founded Date
Data & Forecast
+127%
2 years Growth
1.6K/mo
Search Volume
healthlifestylepersonal-caresupplementseco
Growth
Peaked
Regular
Exploding
Volatility
High
Medium
Low
Speed
Slow
Medium
Exponential
Seasonality
High
Medium
Low
Members Only
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Showing 1-25 of 105 Results

About Vitamins & Supplements

This December, Gruns, Odyssey Elixir, and Create creatine are defining the future of Supplements startups. Gruns, founded in Jan 2023, leads the way with 90.5K monthly searches and +745% growth. Odyssey Elixir, launched in Jan 2020, has also gained attention, posting +463% growth and 1.6K searches per month. Create creatine, founded in Jan 2022, continues to expand its reach with 5.4K monthly searches and +522% growth. These three brands exemplify the strength and diversity of the Supplements startups, showing how quickly innovation can turn into mainstream momentum.

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